Interactions between alprazolam and levonorgestrel have been reported.

Interactions between alprazolam and levonorgestrel have been reported.


This report displays the potential drug interactions between alprazolam and levonorgestrel. No interactions were found between the two drugs. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Alprazolam is a benzodiazepine and is used to treat various conditions. A total of 538 drugs are known to interact with alprazolam.

Levonorgestrel is in the drug classes contraceptives and progestins and is used to treat various conditions. A total of 240 drugs are known to interact with levonorgestrel.

Grapefruit and grapefruit juice may interact with alprazolam and lead to potentially dangerous side effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Do not drink alcohol while taking alprazolam. This medication can increase the effects of alcohol. You may feel more drowsy, dizzy, or tired if you take alprazolam with alcohol. Talk to your doctor or pharmacist if you have any questions or concerns.

Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with levonorgestrel. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication. Major interactions are highly clinically significant and should be avoided; moderate interactions are moderately clinically significant and should usually be avoided; minor interactions are minimally clinically significant and can be monitored; unknown interactions have no known information available.

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