Uses and Side Effects of Amphadase Injection

Uses and Side Effects of Amphadase Injection

Generic name: hyaluronidase (injection) [HYE-al-ure-ON-i-dase]

What is hyaluronidase?

Hyaluronidase is a genetically designed protein used in conjunction with fluids injected into the body to treat dehydration. It can also help the body absorb other injected medications and aid in the visualization of contrast dyes on certain types of x-rays or scans. However, hyaluronidase may also be used for other purposes not listed in this medication guide.


Serious drug interactions can occur when certain medicines are used together with hyaluronidase. It is important to inform your doctor about all current medications before taking hyaluronidase.

Before taking this medicine

Do not use hyaluronidase if you are allergic to it. Your doctor may perform a skin test to determine if you have an allergy to hyaluronidase before administering the medication. Inform your doctor if you are pregnant or breastfeeding.

How is hyaluronidase given?

Hyaluronidase is injected under the skin, into a muscle, or into other tissues of the body. A healthcare provider will administer the injection. Hyaluronidase should not be injected into a vein.

What happens if I miss a dose?

As hyaluronidase is administered in a clinical setting, it is unlikely that you will miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid after receiving hyaluronidase?

Follow your doctor’s instructions regarding any restrictions on food, beverages, or activity.

Hyaluronidase side effects

Seek emergency medical help if you experience signs of an allergic reaction such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. Serious side effects of Amphadase may include swelling in the hands, feet, or other body areas, as well as pain, swelling, itching, or redness where the injection was given. Contact your doctor immediately if you experience any of these symptoms. Other side effects may occur, so it is important to consult your doctor for medical advice. You may also report side effects to the FDA at 1-800-FDA-1088.

What other drugs will affect hyaluronidase?

Inform your doctor about all current medications, including prescription and over-the-counter medicines, vitamins, and herbal products, as they may interact with hyaluronidase.

Frequently asked questions

Additional information about Amphadase (hyaluronidase) can be found in patient resources and professional resources. Related treatment guides are also available.

Further information

Remember to keep all medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Always consult your healthcare provider to ensure that the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

This article was medically reviewed by Alprazolamum Store on Jun 6, 2022 and written by Cerner Multum. The information provided is for educational purposes only and is not intended to replace discussions with a healthcare provider.

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